In New You, Dr. Daryl Gioffre unpacks why popular GLP-1 medications like Ozempic and Wegovy may be triggering unexpected digestive issues like acid reflux, bloating, and pressure. He explains how slowing digestion can create a “traffic jam” in the gut—leading to fermentation, gas buildup, and stomach acid creeping upward.
“Think of your stomach like a highway,” says Dr. Daryl. “GLP-1s slow the cars down… food backs up, fermentation increases, gas is created, and that pressure pushes against the lower esophageal sphincter. When that valve opens, acid comes up. That’s reflux.”

